Publications Prof. Andreas Liese | Institute of Technical Biocatalysis

2023

- - - - A. Malvis Romero, J. J. Picado Morales, L. Klose, A. Liese
        Enzyme-Assisted Extraction of Ulvan from the Green Macroalgae Ulva fenestrata
        Molecules (2023)
        DOI: 10.3390/molecules28196781
      - G. V. Sayoga, V. S. Bueschler, H. Beisch, D. Holtmann, A. P. Zeng, B. Fiedler, D. Ohde, A. Liese
        Application of the all-in-one electrode for in situ H2O2 generation in hydroxylation catalyzed by unspecific peroxygenase from Agrocybe aegerita
        Molecular Catalysis (2023)
        DOI: 10.1016/j.mcat.2023.113325
      - L. Klose, N. Meyer-Heydecke, S. Wongwattanarat, J. Chow, P. Pérez García, C. Carré, W. Streit, G. Antranikian, A. Malvis Romero, A. Liese
        Towards Sustainable Recycling of Epoxy-Based Polymers: Approaches and Challenges of Epoxy Biodegradation
        Polymers (2023)
        DOI: 10.3390/polym15122653
      - A. Malvis Romero, F. Brozio, S. Kammler, C. Burkhardt, L. Baruth, M. Kaltschmitt,
        G. Antranikian, A. Liese
        Enzyme-assisted extraction of alginate from beach wrackfucus vesiculosus
        Chemie Ingenieur Technik (2023)
        DOI: 10.1002/cite.202200173

2022

- - - - B. Thomas, D. Ohde, S. Matthes, P. Bubenheim, K. Terasaka, M. Schlüter, A. Liese
        Enhanced enzyme stability and gas utilization by microbubble aeration applying microporous aerators
        Catalysis Science & Technology (2022)
        DOI: 10.1039/D2CY01761J
      - L. Geuer, G. Liese, A. Liese, S. Perret, A. Schlindwein, R. Ulber
        „Experimente aus der Kiste“ – Kultivierung von Mikroorganismen; Biotechnologische Ansätze mit Alltagsbezug für den forschungsorientierten MINT-Unterricht
        Chemie in unserer Zeit
      - A. E. Ünlü, B. Prasad, K. Anavekar, P. Bubenheim, A. Liese
        The effect of natural deep eutectic solvents on laccase activity and oligomerization of rutin
        Taylor & Francis, Biocatalysis and Biotransformation (2022) online
        DOI: 10.1080/10242422.2022.2120391
      - J.-O. Kundoch, T. Hassemer, D. Ohde, A. Liese
        Novel technique for monitoring thermal unfolding of enzymes in crude mixtures
        Chemie Ingenieur Technik 94 (9) (2022) 1276-1277
        DOI: 10.1002/cite.202255197
      - J. A. Reich, M. Aßmann, K. Hölting, P. Bubenheim, J. Kuballa, A. Liese
        Shift of reaction equilibrium at high pressure in the continuous synthesis of neuraminic acid
        Beilstein Journal of Organic Chemistry 18 (2022) 567-579
        DOI: 10.3762/bjoc.18.59
      - N. Widderich, N. Mayer, A. J. Ruff, B. Reckels, F. Lohkamp, C. Visscher, U. Schwaneberg, M. Kaltschmitt, A. Liese, P. Bubenheim
        Conditioning of feed material prior to feeding: Approaches for a sustainable phosphorus utilization
        Sustainability 14 (2022) 3998
        DOI: 10.3390/su14073998
      - B. O. Burek, A. W. H. Dawood, F. Hollmann, A. Liese, D. Holtmann
        Process intensification as game changer in enzyme catalysis
        Frontiers in Catalysis 2 (2022) Online, 21 March 2022
        DOI: 10.3389/fctls.2022.858706
      - D. Eixenberger, A.-F. Carballo-Arce, J.-R. Vega-Baudrit, H. Trimino-Vazquez , L. R. Villegas-Penaranda , A. Stöbener, F. Aguilar, J.-A. Mora-Villalobos, M. Sandoval-Barrantes, P. Bubenheim, A. Liese
        Tropical agroindustrial biowaste revalorization through integrative biorefineries – review part II: pineapple, sugarcane and banana by-products in Costa Rica
        Biomass conversion and biorefinery (2022) Online, 08 May 2022
        DOI: 10.1007/s13399-022-02721-9

2021

- - - - J.-A. Mora-Villalobos, F. Aguilar, A. Francis Carballo-Arce, J.-R. Vega-Baudrit, H. Trimino-Vazquez, L. Villegas-Penaranda, A. Stöbener, D. Eixenberger, P. Bubenheim, M. Sandoval, A. Liese
        Tropical agroindustrial biowaste revalorization through integrative biorefineries—review part I: coffee and palm oil by-products
        Biomass Conversion and Biorefinery (2021) ACCEPTED
      - G. Liese, J. Husung
        Mit Hefe und Netiquette
        Digital unterrichten BIOLOGIE 10 (2021) 4-5
      - C. Plass, N. Adebar, R. Hiessl, J. Kleber, A. Grimm, A. Langsch, R. Otter, A. Liese, H. Gröger
        Structure-performance guided design of sustainable plasticizers from bio-renewable feedstocks
        European Journal of Organic Chemistry (2021) Online
        DOI: 10.1002/ejoc.202101014
      - F. Meyer, J. Johannsen, A. Liese, G. Fieg, P. Bubenheim, T. Waluga
        Evaluation of process integration for the intensification of a biotechnological process
        Chemical Engineering and Processing: Process Intensification 167 (2021) 108506
      - J. Johannsen, F. Meyer, C. Engelmann, A. Liese, G. Fieg, P. Bubenheim, T. Waluga
        Multi‐enzyme cascade reaction in a miniplant two‐phase‐system : Model validation and mathematical optimization
        AIChE Journal 67 (4) (2021) 1-10
        DOI: 10.1002/aic.17158
      - D. Ohde, B. Thomas, S. Matthes, S. Tanaka, P. Bubenheim, K. Terasaka, M. Schlüter, A. Liese
        Microbubble enhanced mass transfer efficiency of CO2 capture utilizing aqueous triethanolamine for enzymatic resorcinol carboxylation
        RSC Advances 11 (7) (2021) 4087-4096
        DOI: 10.1039/D0RA08690H
      - B. Thomas, D. Ohde, S. Matthes, C. Engelmann, P. Bubenheim, K. Terasaka, M. Schlüter, A. Liese
        Comparative investigation of fine bubble and macrobubble aeration on gas utility and biotransformation productivity
        Biotechnology & Bioengineering 118 (1) (2021) 130-141
        DOI: 10.1002/bit.27556
      - D. Ohde, B. Thomas, P. Bubenheim, A. Liese
        Enhanced CO2 fixation in the biocatalytic carboxylation of resorcinol: Utilization of amines for amine scrubbing and in situ product precipitation
        Biochemical Engineering Journal 166 (2021) 107825
        DOI: 10.1016/j.bej.2020.107825

2020

- - - - S. Matthes, B. Thomas, D. Ohde, M. Hoffmann, P. Bubenheim, A. Liese, S. Tanaka, K. Terasaka, M. Schlueter
        Hydrodynamic and mass transfer correlation in a microbubble aerated stirred tank reactor
        Journal of Chemical Engineering of Japan 53 (10) (2020) 577-584
        DOI: 10.1252/jcej.19we181
      - C. Engelmann, J. Johannsen, T. Waluga, G. Fieg, A. Liese, P. Bubenheim
        A multi-enzyme cascade for the production of high value aromatic compounds
        Catalysts 10 (10) (2020) 1216
        DOI: 10.3390/catal10101216
      - Perz, S. Bormann, H-G. Hennemann, F. Nissen, F. Hollmann, D. Holtmann, P. Bubenheim, A. Liese
        Biocatalytic oxyfunctionalization of butane in a bubble‐column reactor
        Chemie Ingenieur Technik 92 (9) (2020) 1211
        DOI: 10.1002/cite.202055313
      - B. Thomas, D. Ohde, S. Matthes, C. Engelmann, P. Bubenheim, K. Terasaka, M. Schlüter, A. Liese
        Comparative investigation of fine bubble and macrobubble aeration on gas utility and biotransformation productivity
        Biotechnology & Bioengineering (2020) ACCEPTED
        DOI: 10.1002/bit.27556
      - D. Ohde, B. Thomas, P. Bubenheim, A. Liese
        Enhanced CO2 fixation in the biocatalytic carboxylation of resorcinol: Utilization of amines for amine scrubbing and ISPR
        Biochemical Engineering Journal (2020) ACCEPTED
      - G. Liese, J. Husung, I. Klose, J. Lehmann, A. Liese
        Digitale und analoge MINT-Bildungskonzepte, die Schule, Hochschule und Unternehmen zusammenbringen
        Chemie Ingenieur Technik 92 (9) (2020) 1185
        DOI: 10.1002/cite.202055136
      - K. Schlipköter, T. Betke, J. Kleber, H. Gröger, A. Liese
        Fatty alcohol synthesis from fatty acids at mild temperature by subsequent enzymatic esterification and metal-catalyzed hydrogenation
        Organic & Biomolecular Chemistry 18 (39) (2020) 7862-7867
        DOI: 10.1039/d0ob01561J
      - C. Plass, R. Hiessl, J. Kleber, A. Grimm, A. Langsch, R. Otter, A. Liese, H. Gröger
        Towards bio-based plasticizers with reduced toxicity: Synthesis and performance testing of a 3-methylphthalate
        Sustainable Chemistry and Pharmacy 18 (2020) 100319
        DOI: 10.1016/j.scp.2020.100319
      - R. Hiessl, L. Hennecke, C. Plass, J. Kleber, S. Wahlefeld, R. Otter, H. Gröger, A. Liese
        FTIR based kinetic characterisation of an acid-catalysed esterification of 3-methylphthalic anhydride and 2-ethylhexanol
        Analytical Methods 12 (24) (2020) 3137-3144
        DOI: 10.1039/d0ay00686f
      - S. Lütz, A. Liese
        30 Jahre sichere Gentechnik in Deutschland
        30 years of safe genetic engineering in Germany
        Angewandte Chemie 132 (33) (2020) 13772-13773
        Angewandte Chemie Int. Ed. 59 (33) (2020) 13668-13669
        DOI: 10.1002/ange.202006430
        DOI: 10.1002/anie.202006430
      - N. Büscher, C. Spille, J. K. Kracht, G. V. Sayoga, A. W. H. Dawood, M. I. Maiwald, D. Herzog, M. Schlüter, A. Liese
        Countercurrently operated reactive extractor with an additively manufactured enzyme carrier structure
        Organic Process Research & Development (2020)
        DOI: 10.1021/acs.oprd.0c00205
      - F. Perz, S. Bormann, R. Ulber, M. Alcalde, P. Bubenheim, F. Hollmann, D. Holtmann, A. Liese
        Enzymatic oxidation of butane to 2-butanol in a bubble column
        ChemCatChem 12 (2020) 3666-3669
        DOI: 10.1002/cctc.202000431
      - Johannsen, C. Engelmann, A. Liese, G. Fieg, P. Bubenheim, T. Waluga
        Pilot-scale operation of a multi-enzymatic cascade reaction in a multiphase system
        Chemical Engineering Transactions 79 (2020) 25-30
        DOI: 10.3303/CET2079005
      - N. Noirungsee, S. Hackbusch, J. Viamonte, P. Bubenheim, A. Liese, R. Müller
        Influence of oil, dispersant and pressure on microbial communities from the Gulf of Mexico
        Scientific Reports (2020) 10:7079
        DOI: 10.1038/s41598-020-63190-6
      - C. Engelmann, N. Ekambaram, J. Johannsen, O. Fellechner, T. Waluga, G. Fieg, A. Liese, P. Bubenheim
        Enzyme immobilization on synthesized nanoporous silica particles and their application in a bi-enzymatic reaction
        ChemCatChem (2020)
        DOI: 10.1002/cctc.201902293 (ACCEPTED/Online open AID – 16674649)
      - G. Sluyter, J. Kleber, F. Perz, B. Grund, S. Leuchs, S. Sieberz, P. Bubenheim, O. Thum, A. Liese
        Fermentative Oxidation of Butane in Bubble Column Reactors
        Biochemical Engineering Journal (2020)
        DOI: 10.1016/j.bej.2020.107486

2019

- - - - D. Ohde, B. Thomas, S. Matthes, Z. Percin, C. Engelmann, P. Bubenheim, K. Terasaka, M. Schlüter, A. Liese
        Fine Bubble‐based CO 2 Capture Mediated by Triethanolamine Coupled to Whole Cell Biotransformation
        Chemie Ingenieur Technik 91 (2019) 1822-1826
        DOI: 10.1002/cite.201900113
      - A. Stöbener, M. Fabuel Ortega, C. J. Bolten, E. Ananta, S. Nalur, A. Liese
        In situ Monitoring of the Biocatalyzed Partial Hydrolysis of Cocoa Butter and Palm Oil Fraction
        International Journal of Food Science and Technology 6 (2019) 32422
        DOI: 10.1111/ijfs.14366
      - S. Hackbusch, N. Noirungsee, J. Viamonte Dominguez, X. Sun, P. Bubenheim, J. Kostka, R. Mueller, A. Liese
        Influence of pressure and dispersant on oil biodegradation by a newly isolated Rhodococcus strain from deep-sea sediments of the Gulf of Mexico
        Marine Pollution Bulletin (2019) 110683
        DOI: 10.1016/j.marpolbul.2019.110683
      - M. Pätzold, S. Siebenhaller, S. Kara, A. Liese, C. Syldatk, D. Holtmann
        Deep eutectic solvents as efficient solvents in biocatalysis
        Trends in Biotechnology 37 (2019) 943-959
        DOI: 10.1016/j.tibtech.2019.03.007
      - N. Büscher, G. Sayoga, K. Rübsam, F. Jakob, U. Schwaneberg, S. Kara, A. Liese
        Biocatalyst immobilization by anchor peptides on an additively manufacturable material
        Organic Process Research & Development 23 (2019) 1852-1859
        DOI: 10.1021/acs.oprd.9b00152
      - A. Stöbener, U. Naefken, J. Kleber, A. Liese
        Determination of trace amounts with ATR FTIR spectroscopy and chemometrics: 5-(hydroxymethyl)furfural in honey
        Talanta 204 (2019) 1-5
        DOI: 10.1016/j.talanta.2019.05.092
      - M. Pätzold, B. O. Burek, A. Liese, J. Z. Bloh, D. Holtmann
        Product recovery of an enzymatically synthesized (-)-menthol ester in a deep eutectic solvent
        Bioprocess and Biosystems Engineering 42 (2019) 1385-1389
        DOI: 10.1007/s00449-019-02125-6
      - M. Pätzold, A. Weimer, A. Liese, D. Holtmann
        Optimization of solvent-free enzymatic esterification in eutectic substrate reaction mixture
        Biotechnology Reports 24 (2019) e00333
        DOI: 10.1016/j.btre.2019.e00333

2018

- - - - Hümmer, S. Kara, A. Liese, I. Huth, J. Schrader, D. Holtmann
        Synthesis of (-)-menthol fatty acid esters in and from (-)-menthol and fatty acids – novel concept for lipase catalyzed esterification based on eutectic solvents
        Molecular Catalysis 458 (2018) 67-72
        DOI: 10.1016/j.mcat.2018.08.003
      - S. Molla, A. Himmelspach, R. Wohlgemuth, E. T.K. Haupt, A. Liese
        Mechanistic and kinetics elucidation of Mg²⁺/ATP molar ratio effect on glycerol kinase
        Molecular Catalysis 445 (2018) 36-42
        DOI: 10.1016/j.mcat.2017.11.006

2017

- - - - Pesci, P. Gurikov, A. Liese, S. Kara
        Amine-mediated enzymatic carboxylation of phenols using CO2 as substrate increases equilibrium conversions and reaction rates
        Biotechnology Journal 12 (2017) 1-7
        DOI: 10.1002/biot.201700332
      - Gebhard, B. Neuer, G.A. Luinstra, A. Liese
        Enzyme- and metal-catalyzed synthesis of a new biobased polyester
        Organic Process Research & Development 21 (9) (2017) 1245-1252
        DOI: 10.1021/acs.oprd.6b00418
      - Ezgi Ünlü, B. Prasad, K. Anavekar, P. Bubenheim, A. Liese
        Investigation of a green process for the polymerization of catechin
        Preparative biochemistry & biotechnology 47 (9) (2017) 918-924
        DOI: 10.1080/10826068.2017.1365241
      - Aßmann, A. Stöbener, C. Mügge, S. K. Gaßmeyer, L. Hilterhaus, R. Kourist, A. Liese, S. Kara
        Reaction engineering of biocatalytic (S)-naproxen synthesis integrating in-line process monitoring by Raman spectroscopy
        Reaction Chemistry & Engineering 33 (5) (2017) 302
        DOI: 10.1039/c7re00043j
      - S. Kuhn, G. Sluyter, M.-A. Christlieb, R. Heils, A. Stöbener, J. Kleber, I. Smirnova, A. Liese
        In Situ Separation of the Chiral Target Compound (S)-2-Pentanol in Biocatalytic Reactive Distillation
        Industrial & Engineering Chemistry Research 56 (22) (2017) 6451–6461
        DOI: 10.1021/acs.iecr.7b01163
      - L. Pesci, M. Baydar, S. Glueck, K. Faber, A. Liese, S*/*. Kara
        Development and scaling-up of the fragrance compound 4-Ethylguaiacol synthesis via a two-step chemo-enzymatic reaction sequence
        Organic Process Research & Development 21 (1) (2017) 85-93
        DOI: 10.1021/acs.oprd.6b00362
      - F. Uthoff, A. Reimer, A. Liese, H. Gröger
        Enzymatic resolution of an amine under solvent-free conditions with diethyl malonate as reagent for acylation
        Sustainable Chemistry and Pharmacy 5 (2017) 42-45
        DOI: 10.1016/j.scp.2016.12.002
      - S. Wedde, P. Rommelmann, C. Scherkus, S. Schmidt, U. T. Bornscheuer, A. Liese, H. Gröger
        An alternative approach towards poly-ε-caprolactone through a chemoenzymatic synthesis: combined hydrogenation, bio-oxidations and polymerization without the isolation of intermediates
        Green Chemistry 19 (2017) 1286-1290
        DOI: 10.1039/c6gc02529c
      - G. S. Molla, B. M. Kinfu, J. Chow, W. Streit, R. Wohlgemuth, A. Liese
        Bioreaction engineering leading to efficient synthesis of L-glyceraldehyde-3-phosphate
        Biotechnology Journal 12 (3) (2017)
        DOI: 10.1002/biot.201600625
      - D. Sellin, R. Hiessl, M. Bothe, J. Timmermann, M. Becker, M. Schlüter, A. Liese
        Simultaneous local determination of mass transfer and residence time distributions in organic multiphase systems
        Chemical Engineering Journal 321 (2017) 635-641
        DOI: 10.1016/j.cej.2017.03.150
      - C. Scherkus, S. Schmidt, U. T. Bornscheuer, H. Gröger, S. Kara, A. Liese
        Kinetic insights into ε-caprolactone synthesis: improvement of an enzymatic cascade reaction
        Biotechnology and Bioengineering 114 (6) (2017) 1215-1221
        DOI: 10.1002/bit.26258
      - M. Aßmann, C. Mügge, S. K. Gaßmeyer, J. Enoki, L. Hilterhaus, R. Kourist, A. Liese, S. Kara
        Improvement of the process stability of arylmalonate decarboxylase by immobilization for biocatalytic profen synthesis
        Frontiers in Microbiology 8 (2017) 448
        DOI: 10.3389/fmicb.2017.00448
      - R. Wohlgemuth, A. Liese, W. Streit
        Biocatalytic Phosphorylations of Metabolites: Past, Present and Future
        Trends in Biotechnology 35 (5) (2017) 452-465
        DOI: 10.1016/j.tibtech.2017.01.005

2016

- - - - K. Gaßmeyer, J. Wetzig, C. Mügge, M. Assmann, J. Enoki, L. Hilterhaus, R. Zuhse,
        K. Miyamoto, A. Liese, R. Kourist
        Arylmalonate decarboxylase-catalyzed asymmetric synthesis of both enantiomers of optically pure flurbiprofen
        ChemCatChem 8 (5) (2016) 916-921
        DOI: 10.1002/cctc.201501205
      - S. Molla, R. Wohlgemuth, A. Liese
        One-pot enzymatic reaction sequence for the syntheses of D-glyceraldehyde 3-phosphate and l-glycerol 3-phosphate
        Journal of Molecular Catalysis B: Enzymatic, 124 (2016) 77-82
        DOI: 10.1016/j.molcatb.2015.12.004
      - S. Molla, P. J. Venkatesh, A. Liese
        Single-pot enzymatic reaction sequence for the synthesis of D -glyceraldehyde-3-phosphate
        Chemie Ingenieur Technik, 86 (9) (2014), 1424
        DOI: 10.1002/cite.201450599
      - Baum, E. Ritter, I. Smirnova, M. Schilling, A. Liese
        The role of phase behavior in the enzyme catalyzed synthesis of glycerol monolaurate
        RSC Advances 6 (38) (2016) 32422-32429
        DOI: 10.1030/c6ra05181b
      - N. Mitrev, A. Y. Mehandzhiyski, D. I. Batovska, A. Liese, B. Galunsky
        Original enzyme-catalyzed synthesis of chalcones: utilization of hydrolase promiscuity
        Journal of the Serbian Chemical Society, 81 (11) (2016) 1231-1237
        DOI: 10.2298/JSC160422069M
      - Weiland-Bräuer, M. J. Kisch, N. Pinnow, A. Liese, R. A. Schmitz
        Highly effective inhibition of biofilm formation by the first metagenome-derived AI-2 quenching enzyme
        Frontiers in Microbiology 7 (2016) article 1098
        DOI: 10.3389/fmicb.2016.01098
      - Pesci, S. Kara, A. Liese
        Evaluation of the substrate scope of benzoic acid (de)carboxylases according to chemical and biochemical parameters
        ChemBioChem 17 (19) (2016) 1845-1850
        DOI: 10.1002/cbic.201600333
      - Heils, X. Hu, A. Liese, I. Smirnova
        In situ production and renewal of biocatalytic coatings for use in enzymatic reactive distillation
        Chemical Engineering Journal 306 (2016) 992-1000
        DOI: 10.1016/j.cej.2016.08.031
      - Brummund, M. Müller, T. Schmitges, I. Kaluzna, D. Mink, L. Hilterhaus, A. Liese
        Process development for oxidations of hydrophobic compounds applying cytochrome P450 monooxygenases in-vitro
        Journal of Biotechnology 233 (2016) 143-150
        DOI: 10.1016/j.jbiotec.2016.07.002
      - Elleuche, P. Esselun, R. Grote, B. Klippel, A. Krüger, A. Liese, M. Ostrop, C. Schäfers, C. Schröder, G. Antranikian
        8th International Congress on Biocatalysis (biocat2016), Hamburg, Germany, 28th August – 1st September, 2016
        Catalysts 6 (10) (2016) 160
        DOI: 10.3390/catal6100160