Publications Prof. Andreas Liese


2017

  • Aßmann, A. Stöbener, C. Mügge, S. K. Gaßmeyer, L. Hilterhaus, R. Kourist, A. Liese, S. Kara
    Reaction engineering of biocatalytic (S)-naproxen synthesis integrating in-line process monitoring by Raman spectroscopy
    Reaction Chemistry & Engineering 33 (5) (2017) 302
    DOI: 10.1039/c7re00043j
  • S. Kuhn, G. Sluyter, M.-A. Christlieb, R. Heils, A. Stöbener, J. Kleber, I. Smirnova, A. Liese
    In Situ Separation of the Chiral Target Compound (S)-2-Pentanol in Biocatalytic Reactive Distillation
    Industrial & Engineering Chemistry Research 56 (22) (2017) 6451–6461
    DOI: 10.1021/acs.iecr.7b01163
  • L. Pesci, M. Baydar, S. Glueck, K. Faber, A. Liese, S*/*. Kara
    Development and scaling-up of the fragrance compound 4-Ethylguaiacol synthesis via a two-step chemo-enzymatic reaction sequence
    Organic Process Research & Development 21 (1) (2017) 85-93
    DOI: 10.1021/acs.oprd.6b00362
  • F. Uthoff, A. Reimer, A. Liese, H. Gröger
    Enzymatic resolution of an amine under solvent-free conditions with diethyl malonate as reagent for acylation
    Sustainable Chemistry and Pharmacy 5 (2017) 42-45
    DOI: 10.1016/j.scp.2016.12.002
  • S. Wedde, P. Rommelmann, C. Scherkus, S. Schmidt, U. T. Bornscheuer, A. Liese, H. Gröger
    An alternative approach towards poly-ε-caprolactone through a chemoenzymatic synthesis: combined hydrogenation, bio-oxidations and polymerization without the isolation of intermediates
    Green Chemistry 19 (2017) 1286-1290
    DOI: 10.1039/c6gc02529c
  • G. S. Molla, B. M. Kinfu, J. Chow, W. Streit, R. Wohlgemuth, A. Liese
    Bioreaction engineering leading to efficient synthesis of L-glyceraldehyde-3-phosphate
    Biotechnology Journal 12 (3) (2017)
    DOI: 10.1002/biot.201600625
  • D. Sellin, R. Hiessl, M. Bothe, J. Timmermann, M. Becker, M. Schlüter, A. Liese
    Simultaneous local determination of mass transfer and residence time distributions in organic multiphase systems
    Chemical Engineering Journal 321 (2017) 635-641
    DOI: 10.1016/j.cej.2017.03.150
  • C. Scherkus, S. Schmidt, U. T. Bornscheuer, H. Gröger, S. Kara, A. Liese
    Kinetic insights into ε-caprolactone synthesis: improvement of an enzymatic cascade reaction
    Biotechnology and Bioengineering 114 (6) (2017) 1215-1221
    DOI: 10.1002/bit.26258
  • M. Aßmann, C. Mügge, S. K. Gaßmeyer, J. Enoki, L. Hilterhaus, R. Kourist, A. Liese, S. Kara
    Improvement of the process stability of arylmalonate decarboxylase by immobilization for biocatalytic profen synthesis
    Frontiers in Microbiology 8 (2017) 448
    DOI: 10.3389/fmicb.2017.00448
  • R. Wohlgemuth, A. Liese, W. Streit
    Biocatalytic Phosphorylations of Metabolites: Past, Present and Future
    Trends in Biotechnology 35 (5) (2017) 452-465
    DOI: 10.1016/j.tibtech.2017.01.005

2016

  • K. Gaßmeyer, J. Wetzig, C. Mügge, M. Assmann, J. Enoki, L. Hilterhaus, R. Zuhse,
    K. Miyamoto, A. Liese, R. Kourist
    Arylmalonate decarboxylase-catalyzed asymmetric synthesis of both enantiomers of optically pure flurbiprofen
    ChemCatChem 8 (5) (2016) 916-921
    DOI: 10.1002/cctc.201501205
  • S. Molla, R. Wohlgemuth, A. Liese
    One-pot enzymatic reaction sequence for the syntheses of D-glyceraldehyde 3-phosphate and l-glycerol 3-phosphate
    Journal of Molecular Catalysis B: Enzymatic, 124 (2016) 77-82
    DOI: 10.1016/j.molcatb.2015.12.004
  • S. Molla, P. J. Venkatesh, A. Liese
    Single-pot enzymatic reaction sequence for the synthesis of D -glyceraldehyde-3-phosphate
    Chemie Ingenieur Technik, 86 (9) (2014), 1424
    DOI: 10.1002/cite.201450599
  • Baum, E. Ritter, I. Smirnova, M. Schilling, A. Liese
    The role of phase behavior in the enzyme catalyzed synthesis of glycerol monolaurate
    RSC Advances 6 (38) (2016) 32422-32429
    DOI: 10.1030/c6ra05181b
  • N. Mitrev, A. Y. Mehandzhiyski, D. I. Batovska, A. Liese, B. Galunsky
    Original enzyme-catalyzed synthesis of chalcones: utilization of hydrolase promiscuity
    Journal of the Serbian Chemical Society, 81 (11) (2016) 1231-1237
    DOI: 10.2298/JSC160422069M
  • Weiland-Bräuer, M. J. Kisch, N. Pinnow, A. Liese, R. A. Schmitz
    Highly effective inhibition of biofilm formation by the first metagenome-derived AI-2 quenching enzyme
    Frontiers in Microbiology 7 (2016) article 1098
    DOI: 10.3389/fmicb.2016.01098
  • Pesci, S. Kara, A. Liese
    Evaluation of the substrate scope of benzoic acid (de)carboxylases according to chemical and biochemical parameters
    ChemBioChem 17 (19) (2016) 1845-1850
    DOI: 10.1002/cbic.201600333
  • Heils, X. Hu, A. Liese, I. Smirnova
    In situ production and renewal of biocatalytic coatings for use in enzymatic reactive distillation
    Chemical Engineering Journal 306 (2016) 992-1000
    DOI: 10.1016/j.cej.2016.08.031
  • Brummund, M. Müller, T. Schmitges, I. Kaluzna, D. Mink, L. Hilterhaus, A. Liese
    Process development for oxidations of hydrophobic compounds applying cytochrome P450 monooxygenases in-vitro
    Journal of Biotechnology 233 (2016) 143-150
    DOI: 10.1016/j.jbiotec.2016.07.002
  • Elleuche, P. Esselun, R. Grote, B. Klippel, A. Krüger, A. Liese, M. Ostrop, C. Schäfers, C. Schröder, G. Antranikian
    8th International Congress on Biocatalysis (biocat2016), Hamburg, Germany, 28th August – 1st September, 2016
    Catalysts 6 (10) (2016) 160
    DOI: 10.3390/catal6100160
  • Scherkus, S. Schmidt, U. T. Bornscheuer, H. Gröger, S. Kara, A. Liese
    A fed-batch synthetic strategy for a three-step enzymatic synthesis of poly-e-caprolactone
    ChemCatChem 8 (22) (2016) 3446-3452
    DOI: 10.1002/cctc.201600806
  • Kern, A. Himmelspach, K. Grammann, O. Thum, A. Liese
    Process characterization studies for solvent-free simultaneous epoxidation and transesterification of fatty acid methy esters
    Organic Process Research & Development 20 (2016) 1930-1936
    (DOI: 10.1021/acs.oprd.6b00254)

2015

  • L. Pesci, S. Glück, P. Gurikov, I. Smirnova, K. Faber, A. Liese
    Biocatalytic Carboxylation of Phenol Derivatives: Kinetics and Thermodynamics of the Biological Kolbe-Schmitt Synthesis
    FEBS Journal 282 (2015) 1334-1345
    DOI: 10.1111/febs.13225
  • R. Heils, J.-H. Jensen, S. Wichert, N. Behrens, M. Fabuel-Ortega, A. Liese, I. Smirnova
    Enzymatic Reactive Distillation: Kinetic Resolution of rac-2-Pentanol with Biocatalytic Coatings on Structured Packings
    Ind. Eng. Chem. Res. 54 (38) (2015) 9458–9467
    DOI: 10.1021/acs.iecr.5b02802
  • S. Schmidt, H. C. Büchsenschütz, C. Scherkus, A. Liese, H. Gröger, U. T. Bornscheuer
    Biocatalytic Access to Chiral Polyesters by an Artificial Enzyme Cascade Synthesis
    ChemCatChem 7 (2015) 3951-3955
    DOI: 10.1002/cctc.201500823
  • M. Berheide, S. Kara, A. Liese
    Reversibility of Asymmetric Catalyzed C–C Bond Formation by Benzoylformate Decarboxylase
    Catalysis Science & Technology (2015)
    5 (2015) 2418-2426 DOI: 10.1039/C4CY00171K
  • M. Pöhnlein, J. Ulrich, F. Kirschhöfer, M. Nusser, C. Muhle-Goll, B. Kannengiesser, G. Brenner-Weiß, B. Luy, A. Liese, C. Syldatk, R. Hausmann
    Lipase-catalyzed synthesis of glucose-6-O-hexanoate in deep eutectic solvents
    European Journal of Lipid Science and Technology
    117 (2) (2015) 161-166 DOI: 10.1002/ejlt.201400459
  • S. Schmidt, C. Scherkus, J. Muschiol, U. Menyes, T. Winkler, W. Hummel, H. Gröger, A. Liese, H.-G. Herz, U. T. Bornscheuer
    An Enzyme Cascade Synthesis of Oligo-ε-Caprolactone
    Angewandte Chemie Int. Ed.
    54 (2015) 1-5 DOI: 10.1002/anie.201410633

2014

  • G. S. Molla, P. J. Venkatesh, A. Liese
    Single-Pot Enzymatic Reaction Sequence for the Synthesis of D -Glyceraldehyde-3-Phosphate
    Chemie Ingenieur Technik, 86 (9) (2014), 1424
    DOI: 10.1002/cite.201450599
  • D. Kaufhold, J. Fagaschewski, D. Sellin, S. Strompen, A. Liese, L. Hilterhaus
    Novel µ-Membrane Module for the Online Determination of the Free Fatty Acid Content in the Dispersed Phase of oil in water Emulsions
    Analytical and Bioanalytical Chemistry (2014) 406 (13) 3157-66
    DOI: 10.1007/s00216-014-7740-9
  • J. M. Kisch, C. Utpatel, L. Hilterhaus, W. R. Streit, A. Liese
    Pseudomonas aeruginosa Biofilm Growth Inhibition on Medical Plastic Materials by Immobilized Esterases and Acylase
    ChemBioChem (online) (2014)
    DOI: 10.1002/cbic.201400023
  • C. Scherkus, A. Liese, H. Gröger, U. Kragl, U. Bornscheuer, U. Menyes
    Prozessentwicklung zur enzymatischen Synthese eines biologisch abbaubaren Polymers
    Chemie Ingenieur Technik (2014)
    86 (9) (2014) 1424-1425 DOI: 10.1002/cite.201450586
  • S. Baum, M. Schilling, D. Sellin, A. Liese
    Steuerung der Reaktionsselektivität von Biotransformationen mittels Online-FTIR-Analytik
    Chemie Ingenieur Technik (2014)
    86 (9) (2014) 1583-1584 DOI: 10.1002/cite.201450600
  • F. Rieckenberg, K. Götz, L. Hilterhaus, A. Liese, A.-P. Zeng
    Strategies for reliable and improved large-scale production of Pyrococcus furiosus with integrated purification of hydrogenase I
    Bioprocess Biosyst Eng.
    37 (12) (2014) 2475-82 DOI: 10.1007/s00449-014-1225-2

2013

  • S. Cumana, J. Simons, A. Liese, L. Hilterhaus, I. Smirnova
    Immobilization of glucose 6-phosphate dehydrogenase in silica-based hydrogels: a comparative study
    Journal of Molecular Catalysis B: Enzymatic 85–86 (2013) 220-228
    DOI: 10.1016j.molcatb.2012.09.014
  • K. Götz, A. Liese, M. Ansorge-Schumacher, L. Hilterhaus
    A chemo-enzymatic route to synthesize (S)-gamma-valerolactone from levulinic acid
    Appl Microbiol Biotechnol 97 (9) (2013) 3865-3873
    DOI: 10.1007/s00253-012-4652-5
  • D. Kaufhold, F. Kopf, C. Wolff, S. Beutel, L. Hilterhaus, M. Hoffmann, T. Scheper, M. Schlüter, A. Liese
    Reaktive Absorption von Kohlenstoffdioxid in helikalen Hohlfasermembrankontaktoren
    Chemie Ingenieur Technik, 85 (4) (2013) 476-483
    DOI: 10.1002/cite.201200240
  • A. Liese, L. Hilterhaus
    Evaluation of immobilized enzymes for industrial applications
    Chemical Society Reviews, 42 (2013) 6236-6249
    DOI: 10.1039/C3CS35511J
  • J. Gebhard, D. Sellin, L. Hilterhaus, A. Liese
    Online-Analyse von enzymatischen Polykondensationsreaktionen in Blasensäulenreaktoren mittels ATR-FTIR Spektroskopie
    Chemie Ingenieur Technik, 85 (4) (2013) 1-8
    DOI: 10.1002/cite.201200248
  • A. Liese, U. Kragl
    Einfluss der Reaktorkonfiguration auf die Enantioselektivität einer kinetischen Racematspaltung
    Chemie Ingenieur Technik, 85 (6) (2013) 826-832
    DOI: 10.1002/cite.201300011
  • A. Liese
    Die Zukunft liegt in der interdisziplinären Forschung und Entwicklung
    Chemie Ingenieur Technik, 85 (6) (2013) 771
    DOI: 10.1002/cite.201390047
  • S. Strompen, M. Weiß, H. Gröger, L. Hilterhaus, A. Liese
    Development of a continuously operating process for the enantioselective synthesis of a beta-amino acid ester via a solvent-free chemoenzymatic reaction sequence
    Advanced Synthesis Catalysis 355 (11-12) (2013) 2391-2399
    DOI: 10.1002/adsc.201300236
  • B. Opitz, A. Prediger, C. Luder, M. Eckstein, L. Hilterhaus, P. Lindner, S. Beutel, T. Scheper, A. Liese
    In Situ Microscopy for In-line Monitoring of the Enzymatic Hydrolysis
    Analytical Chemistry 85 (17) (2013) 8121-8126
    DOI: 10.1021/ac4008495

2012

  • J. Chow, F. Kovacic, Y. Dall Antonia, U. Krauss, F. Fersini, C. Schmeisser, B. Lauinger, P. Bongen, J. Pietruszka, M. Schmidt, I. Menyes, U. T. Bornscheuer, M. Eckstein, O. Thum, A. Liese, J. Mueller-Dieckmann, K.-E. Jaeger, W. R. Streit
    The Metagenome-Derived Enzymes LipS and LipT Increase the Diversity of Known Lipases
    PLOS ONE 7 (10) (2012) e47665
    DOI:10.1371/journal.pone.0047665
  • R. Heils, A. Sont, P. Bubenheim, A. Liese, I. Smirnova
    Integration of enzymatic catalysts in a reactive distillation column with structured packings
    Industrial & Engineering Chemistry Research, 51 (35) (2012) 11482–11489
    DOI: 10.1021/ie300837v
  • K. T. Schomburg, I. Ardao, K. Götz, F. Rieckenberg, A. Liese, A.-P. Zeng, M. Rarey
    Computational Biotechnology: Prediction of competitive substrate inhibition of enzymes by buffer compounds with protein-ligand docking
    Journal of Biotechnology 161 (2012) 391-401
    DOI: 10.1016/j.jbiotec.2012.08.002
  • D. Kaufhold, F. Kopf, C. Wolff, S. Beutel, L. Hilterhaus, M. Hoffmann, T. Scheper, M. Schlüter, A. Liese
    Generation of Dean vortices and enhancement of oxygen transfer rates in membrane contactors for different hollow fiber geometries
    Journal of Membrane Science 423-424 (2012) 342-347
    DOI: 10.1016/j.memsci.2012.08.035
  • S. Strompen, M. Weiss, T. Ingram, I. Smirnova, H. Gröger, L. Hilterhaus, A. Liese
    Kinetic investigation of a solvent-free, chemoenzymatic reaction sequence towards enantioselective synthesis of a β-amino acid ester
    Biotechnology and Bioengineering 109 (6) (2012) 1479–1489
    DOI: 10.1002/bit.24422
  • S. Cumana, J. Simons, A. Liese, L. Hilterhaus, I. Smirnova
    Immobilization of glucose 6-phosphate dehydrogenase in silica-based hydrogels: a comparative study
    Journal of Molecular Catalysis B: Enzymatic 85–86 (2013) 220-228
    http://dx.doi.org/10.1016/j.molcatb.2012.09.014


2011

  • A. Prediger, A. Bluma, T. Höpfner, P. Lindner, S. Beutel, J. J. Müller, L. Hilterhaus, A. Liese, T. Scheper
    In-situ Mikroskopie zur online-Überwachung von enzymatischen Prozessen
    Chemie Ingenieur Technik 83 (5) (2011) 1-5, DOI: 10.1002/cite.201000203
  • A. Prediger, A. Bluma, T. Höpfner, P. Lindner, S. Beutel, J. J. Müller, L. Hilterhaus, A. Liese, T. Scheper
    In-situ microscopy for online monitoring of enzyme carriers and two-phase processes
    Chemical Engineering & Technology 34 (5) (2011) 837-840,
    DOI: 10.1002/ceat.201000563
  • S. Kara, W. S. Long, M. Berheide, S. Peper, B. Niemeyer, A. Liese
    Influence of reaction conditions on the enantioselectivity of biocatalyzed C–C bond formations under high pressure conditions
    Journal of Biotechnology 152 (3) 87-92, DOI: 10.1016/j.jbiotec.2011.01.020
  • S. Peper, S. Kara, W. S. Long, A. Liese, B. Niemeyer
    Immobilization and characterization of benzoylformatedecarboxylase from Pseudomonas putida on sphericalsilica carrier
    Bioprocess Biosyst Eng, 34 (6) (2011) 671-680, DOI: 10.1007/s00449-011-0516-0
  • S. Kara, J. Müller, A. Liese
    Online analysis methods for monitoring of bioprocesses
    Chemistry Today 29 (2) (2011) 38-41
  • J. Brummund, F. Meyer, A. Liese, R. Eggers, L. Hilterhaus
    Dissolving carbon dioxide in high viscous substrates to accelerate biocatalytic reactions
    Biotechnology & Bioengineering (2011) 108 (11) (2011) 2765-2769, DOI: 10.1002/bit.23230
  • F. Kopf, M. Schlüter, D. Kaufhold, L. Hilterhaus, A. Liese, C. Wolff, S. Beutel, T. Scheper
    Laminares Mischen in Miniatur-Hohlfasermembranreaktoren durch Ausnutzung von Sekundärströmungen (Teil 1)
    Chemie Ingenieur Technik 83 (7) (2011) 1066-1073, DOI: 10.1002/cite.201100044
  • R. Yuryev, S. Strompen, A. Liese
    Coupled (chemo)enzymatic reactions in continuous flow
    Beilstein Journal of Organic Chemistry, 7 (2011) 1449-1469
  • J. Müller, S. Baum, L. Hilterhaus, M. Eckstein, O. Thum, A. Liese
    Simultaneous determination of mono-, di- and triglycerides in multiphase systems by online FT-IR spectroscropy
    Analytical Chemistry 83 (24) (2011) 9321-9327
  • S. Peper, S. Kara, W.S. Long, A. Liese, B. Niemeyer
    Immobilization and characterization of benzoylformate decarboxylase from Pseudomonas putida on spherical silica
    Bioprocess and Biosystems Engineering, DOI 10.1007/s00449-011-0516-0
  • S. Kara, W.S. Long, M. Berheide, S. Peper, B. Niemeyer, A. Liese
    Influence of reaction conditions on the enantioselectivity of biocatalyzed C–C bond formations under high pressure conditions
    Journal of Biotechnology, Vol. 152, Issue 3, 87 – 92, 2011

2010

  • S. Kara, F. Anton, D. Solle, M. Neumann, B. Hitzmann, T. Scheper, A. Liese
    Fluorescence Spectroscopy as a Novel Method for On-line Analysis of Biocatalytic
    C-C Bond Formations
    Journal of Molecular Biocatalysis B: Enzymatic, Vol. 66, 124 – 129, 2010.
  • R. Yuryev, S. Briechle, H. Griengl, A. Liese
    Asymmetric retro-Henry reaction catalyzed by hydroxynitrile lyase from Hevea brasiliensis
    Journal of Molecular Catalysis:B, ChemCatChem 2 (8), 2010, 981-986
  • R. Yuryev, T. Purkarthofer, M. Gruber, H. Griengl, A. Liese
    Kinetic studies of asymmetric Henry reaction catalyzed by hydroxynitrile lyase from Hevea brasiliensis
    Biocatalysis and Biotransformation, December 2010, Vol. 28, No. 5-6: 348-356
  • A. Prediger, A. Bluma, T. Höpfner, P. Lindner, S. Beutel, J. J. Müller, L. Hilterhaus, A. Liese, T. Scheper
    In-situ Mikroskopie zur online-Überwachung von Enzymträgern und Zweiphasenprozessen
    Chemie Ingenieur Technik, DOI: 10.1002/cite.201000203
  • C. Korupp, R. Weberskirch, J.J. Müller, A. Liese, L. Hilterhaus
    Scale up of Lipase Catalyzed Polyester Synthesis
    Organic Process Research and Development (2010) 14 (5) 1118–1124
  • J.J. Müller, M. Neumann, P. Scholl, L. Hilterhaus, M. Eckstein, O. Thum, A. Liese
    Online Monitoring of Biotransformations in High Viscous Multiphase Systems by Means of FT-IR and Chemometrics
    Analytical Chemistry (2010) 82 (14) 6008–6014
  • M. Berheide, S. Peper, S. Kara, W. Sing Long, S. Schenkel, B. Niemeyer, M. Pohl, A. Liese
    Influence of the Hydrostatic Pressure and pH on the Asymmetric 2–Hydroxyketone Formation Catalyzed by Pseudomonas putida Benzoylformate Decarboxylase and Variants thereofBiotechnology & Bioengineering 106 (1) (2010) 18-26

2009

  • R. Yuryev, A. Liese
    Biocatalysis: The Outcast
    ChemCatChem 2 (1) (2009) 103-107
  • R. Yuryev, A. Liese
    Synthesis of a Novel Unsymmetrical Bisoxazoline Ligand with sp²-Bridging Carbon
    Synlett 16 (2009) 2589-2592
  • N. Richter, M Neumann, A. Liese, R. Wohlgemuth, T. Eggert, W. Hummel
    Characterisation of a recombinant NADP-dependent glycerol dehydrogenase from Gluconobacter oxydans and its application in the production of L-glyceraldehyde
    ChemBioChem 10 (11) (2009) 1888-1896
    Marc Bruning, Marco Berheide, Danilo Meyer, Ralph Golbik, Hans Bartunik, Andreas Liese and Kai Tittmann
  • Structural and Kinetic Studies on Native Intermediates and an Intermediate
    Analogue in Benzoylformate Decarboxylase Reveal a Least Motion Mechanism
    with an Unprecedented Short-Lived Predecarboxylation Intermediate
    Biochemistry 48 (15) (2009) 3258-3268
  • P. Krause, L. Hilterhaus, G. Fieg, A. Liese, U. Bornscheuer
    Chemically and enzymatically catalyzed synthesis of C6-C10 alkyl benzoates
    European Journal of Lipid Science and Technology 111 (2009) 194-201

2008

  • F. Hollmann, Y. Gumulya, C. Tölle, A. Liese, O. Thum
    Evaluation of the Laccase from Myceliophthora thermophila as Industrial Biocatalyst
    for Polymerization Reactions
    Macromolecules 41 (22) (2008) 8520-8524
  • N. Kurlemann, A. Liese
    Asymmetric synthesis of chiral 2-hydroxy ketones by coupled biocatalytic alkene oxidation and C-C bond formation
    Journal of Molecular Catalysis B, Enzymatic 61 (2008) 111-116
  • F. R. P. Oliveira, K. Goldberg, A. Liese, B. Hitzmann
    Chemometric modelling for process analyzers using just a single calibration sample
    Chemometrics and Intelligent Laboratory Systems, 94 (2) (2008) 118-122
  • L. Hilterhaus, O. Thum, A. Liese
    Reactor concept for lipase-catalyzed solvent-free conversion of highly viscousreactants forming two-phase systems
    Organic Process Research and Development 12 (4) (2008) 618-625
  • M. Beigi, S. Roller, R. Haag, A. Liese
    Polyglycerol-Supported Co- and Mn-Salen Complexes as Efficient and RecyclableHomogeneous Catalysts for the Hydrolytic Kinetic Resolution of Terminal Epoxides and Asymmetric Olefin Epoxidation
    European Journal of Organic Chemistry 12 (2008) 2135-2141
  • K. Goldberg, A. Krueger, T. Meinhardt, W. Kroutil, B. Mautner, A. Liese
    Novel immobilization routes for the covalent binding of an alcohol dehydrogenase from Rhodococcus ruber DSM 44541
    Tetrahedron: Asymmetry 19 (10) (2008)1171-1173
  • M. Beigi, R. Haag, A. Liese
    Continuous application of polyglycerol supported salen in a membrane reactor: Asymmetric epoxidation of 6-cyano-2,2-dimethylchromene
    Advanced Synthesis & Catalysis (2008) 350 (6) (2008) 919-925
  • L. Hilterhaus, B. Minow, J. Müller, M. Berheide, H. Quitmann, M.Katzer, O. Thum, G. Antranikian, A. P. Zeng and A. Liese
    Practical application of different enzymes immobilized on sepabeads
    Bioprocess and Biosystems Engineering 31 (3) (2008) 183-191
  • P. Domínguez de María, T. Stillger, M. Pohl, A. Liese, H. Gröger, M. Kiesel, H. Trauthwein
    Enantionselective C-C Bond Ligation Using Recombinant E. coli-Whole-Cell Biocatalysts
    Advanced Synthesis & Catalysis 350 (1) (2008) 165-173
  • M. Wolberg, M. Villela Filho, S. Bode, P. Geilenkirchen, R. Feldmann, Andreas Liese, W. Hummel, M. Müller
    Chemoenzymatic Synthesis of the Chiral Side-Chain of Statins – Application of an Alcohol Dehydrogenase Catalysed Ketone Reduction on a Large Scale
    Bioprocess and Biosystems Engineering 31 (3) (2008) 163-171

2007

  • S. Lütz, K. Vuorilehto, A. Liese
    Process development for the electroenzymatic synthesis of (R-)-methylphenylsulfoxide by use of a 3-dimensional electrode
    Biotechnology and Bioengineering 98 (3) (2007) 525-534
  • K. Schroer, U. Mackfeld, I. A. W. Tan, C. Wandrey, S. Bringer-Meyer, A. Weckbecker, W. Hummel, T. Daußmann, R. Pfaller, A. Liese, S. Lütz
    Continuous Asymmetric Ketone Reduction with Recombinant Escherichia coli
    Journal of Biotechnology 132 (4) (2007) 438-444
  • K. Goldberg, K. Schroer, S. Lütz, A. Liese
    Biocatalytic ketone reduction – a powerful tool for the production of chiral alcohols.Part I: Processes with isolated enzymes
    Applied Microbiology and Biotechnology 76 (2) (2007) 237-248
  • K. Goldberg, K. Schroer, S. Lütz, A. Liese
    Biocatalytic ketone reduction – a powerful tool for the production of chiral alcohols.Part II: Whole cell reductions
    Applied Microbiology and Biotechnology 76 (2) (2007) 249-255
  • B. Osterath, N. Rao, S. Luetz, A. Liese
    Technische Anwendung von Enzymen: Weiße Wäsche und Grüne Chemie
    Chemie in unserer Zeit 41 (4) (2007) 324-333
  • L. Hilterhaus, A. Liese
    Building blocks
    Advances in Biochemical Engineering/Biotechnology, 105 (2007) 133-173
  • L. Greiner, S. Laue, J. Wöltinger, A. Liese
    Contionuous asymmetric hydrogenation
    Topics in Current Chemistry, 276 (2007), 111-124

2006

  • K. Goldberg, K. Edegger, W. Kroutil, A. Liese
    Overcoming the thermodynamic limitation in assymetric hydrogen transfer reactions catalyzed by whole cells
    Biotechnology and Bioengineering, 95 (2006) 192-198
  • H. Chakib, S. Roller, M. Beigi, A. Liese, R. Haag
    Polyglycerol Cr-Salen as a high-loading dendritic catalyst for stereoselective Diels-Alder reactions
    Adv. Synth. Cat., 348 (2006) 1760-1771
  • T. Stillger, M. Pohl, C. Wandrey, A. Liese
    Reaction engineering of benzaldehyde lyase catalyzing enantioselective C-C bond formation
    Organic Process Research & Development 10 (6) (2006) 1172-1177
  • Tan AWI, Fischbach M, Huebner H, Buchholz R, Hummel W, Daussmann T, Wandrey C, Liese A.
    Synthesis of enantiopure (5R)-hydroxyhexane-2-one with immobilized whole cells of Lactobacillus kefiri
    Applied Microbiology Biotechnology, 71(3) (2006) 289-293
  • L. Greiner, S. Laue, A. Liese, C Wandrey
    Continuous homogeneos asymmetric-transfer hydrogenation of ketones: Lessons from kinetics
    Chemistry A European Journal, 12 (2006), 1818-1823
  • P. Dominguez de Maria, T. Stillger, M. Pohl, S. Wallert, K. Drauz, H. Gröger, H. Trautwein, A. Liese
    Preparative enantioselective synthesis of benzoins and (R)-2-hydroxy-1-phenylpropanone by using benzaldehyde lyase
    J. Mol Cat B 38 (2006) 43-47
  • R. Busch, T. Hirth, A. Liese, S. Nordhoff, J. Puls, O. Pulz, D. Sell, C. Syldatk, R. Ulber
    Nutzung nachwachsender Rohstoffe in der industriellen Stoffproduktion
    Chemie Ingenieur Technik, 78 (3) (2006) 219-228
  • R. Busch, T. Hirth, A. Liese, S. Nordhoff, J. Puls, O. Pulz, D. Sell, C. Syldatk, R. Ulber
    The utilization of renewable resources in German industrial production
    Biotechnology Journal, 1 (2006) 770-776

2005

  • A. Liese
    Technical application of biological principles in asymmetric catalysis
    Advances in Biochemical Engineering/Biotechnology, 92 (2005) 197-224
  • P. Christophliemk, M. Liauw, A. Liese
    Trendbericht Technische Chemie 2004
    Nachrichten aus der Chemie, 3 (2005) 312-316
  • R. Mertens, A. Liese, C. Wandrey
    Reaktionstechnische Aspekte der enzymatischen Herstellung von NADPH im Enzym-Membran-Reaktor
    Chemie Ingenieur Technik 77(5) (2005) 609-616
  • Camilo E. La Rotta Hernandez, Stephan Lütz, Andreas Liese, Elba P. S. Bon
    Activity and stability of Caldariomyces fumago chloroperoxidase modified by reductive alkylation, amidation and cross-linking
    Enzyme and Microbial Technology 37(6) (2005) 582-588

2004

  • N. Kurlemann, A. Liese
    Immobilization of benzaldehyde lyase and application as heterogeneous catalyst in the continous synthesis of a chiral 2-hydroxy ketone
    Tetrahedron Asymmetry, 15 (2004) 2955-2958
  • R. Mertens, A. Liese
    Biotechnological applications of hydrogenases
    Current Opinion in Biotechnology, 15 (2004) 343-348
  • W. Braun, B. Calmuschi, J. Haberland, W. Hummel, A. Liese, T. Nickel, O. Stelzer, A. Salzer
    Optically active phospholanes as substituents on ferrocene and chromium-arene complexes
    European Journal of Inorganic Chemistry, 11 (2004) 2235-2243
  • S. Lütz, E. Steckhan, A. Liese
    First asymmetric electroenzymatic oxidation catalyzed by a peroxidase
    Electrochemistry Communications 6 (2004) 583-587
  • M. Eckstein, M. V. Filho, A. Liese, U. Kragl
    Use of an ionic liquid in a two-phase system to improve an alcohol dehydrogenase catalysed reduction
    Chemical Communications 9 (2004) 1084-1085
  • D. Degenring, I. Schröder, A. Liese, L. Greiner
    Resolution of 1,2-diols by enzyme catalyzed oxidation with anodic mediated cofactor regeneration in the extractive membrane reactor- Gaining insight by adaptive simulation
    Organic Process Research & Development 8(2) (2004) 213-218
  • A. Rentmeister, C. Hoh, S. Weidner, G. Dräger, L. Elling, A. Liese, C. Wandrey
    Kinetic examination and simulation of GDP-b-l-fucose synthetase reaction using NADPH and NADH
    Biocatalysis and Biotransformations 22(1) (2004) 49-56
  • B. Lingen, M. Pohl, A. S. Demir, A. Liese, M. Mueller
    Enantioselective syntheses of hydroxy ketones via benzoylformate decarboxylase- and benzaldehyde lyase-catalyzed C-C bond formation
    Oxidative Stress and Disease, 11(Thiamine), (2004) 113-129

2003

  • P. S. Dragovich, T. J. Prins, R. Zhou, T. O. Johnson, Y. Hua, H. T. Luu, S. K. Sakata, E. L. Brown, F. C. Maldonado, T. Tuntland, C. A. Lee, S. A. Fuhrman, L. S. Zalman, A. K. Patick, D. A. Matthews, E. Y. Wu, M. Guo, B. C. Borer, N. K. Nayyar, T. Moran, L. Chen, P. A. Rejto, P. W. Rose, M. C. Guzman, E. Z. Dovalsantos, S. Lee, K. McGee, M. Mohajeri, A. Liese, J. Tao, M. B. Kosa, B. Liu, M. R. Batugo, J.-P. R. Gleeson, Z. P. Wu, J. Liu, J. W. Meador, R. A. Ferre
    Structure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. 8. Pharmacological optimization of orally bioavailable 2-pyridone-containing peptidomimetics
    Journal of Medicinal Chemistry 46(21) (2003) 4572-4585
  • L. Greiner, I. Schröder, D.H. Müller and A. Liese
    Utilization of adsorption effects for the continous reduction of NADP+ with molecular hydrogen by Pyrococcus furiosus hydrogenase
    Green Chemistry 5(6) (2003) 697 – 700
  • R. Mertens, L. Greiner, E. C. D. van den Ban, H. B. C. M. Haaker, A. Liese
    Practical applications of hydrogenase I from Pyrococcus furiosus for NADPH generation and regeneration
    Journal of Molecular Catalysis B: Enzymatic 24-25 (2003) 39-52
  • M. Villela Filho, M. Müller, A. Liese, C. Wandrey
    Is the polarity a convenient criterion to guide the choice of solvents for biphasic enzymatic reactions?
    Angewandte Chemie 115(26), 3101-3104
    Angewandte Chemie Int. Ed. 42(26) (2003) 2993-2996
  • L. Greiner, D. Müller, E. van den Ban, J. Wöltinger, C. Wandrey, A. Liese
    Membrane aerated hydrogenation: Enzymatic and chemical homogeneous catalysis
    Advanced Synthesis and Catalysis 345 (2003) 679-683
  • H. Visser, M. Villela Filho, A. Liese, C. Weijers, J. Verdoes
    Construction and characterization of a genetically engineered Escherichia coli strain for the epoxide hydrolase-catalyzed kinetic resolution of epoxides
    Biocatalysis and Biotransformations 21 (2003) 33-40
  • D. Vasic-Racki, U. Kragl, A. Liese
    Benefits of enzyme kinetics modelling
    Chemical and Biochemical Engineering Quarterly 17 (1) (2003) 7-118
  • I. Schröder, E. Steckhan, A. Liese
    In situ NAD(P)+ regeneration using 2,2′-azinobis(3-ethylbenzothiazolin-6-sulfonate) as an electron transfer mediator
    Journal of Electroanalytical Chemistry 541 (2003)109-115
  • D. Vasic-Racki, J. Bongs, U. Schörken, G. A. Sprenger, A. Liese
    Modeling of reaction kinetics for reactor selection in the case of L-erythrulose synthesis
    Bioprocess and Biosystems Engineering 25(5) (2003) 285-290

2002

  • I. Chin-Joe, J. Haberland, A. Straathof, J. Jongejan, A. Liese, J. Heijnen
    Reduction of ethyl 3-oxobutanoate by baker’s yeast under steady state conditions
    Enzyme Microbial Technology 31 (2002) 665-672
  • A. Buchholz, L. Greiner, C. Hoh, A. Liese
    Genetic algorithms as tool for capillary electrophoresis method development
    Journal of Capillary Electrophoresis and Microchip Technology 7(3 & 4) (2002) 51-60
  • J. Haberland, W. Hummel, T. Dausmann, A. Liese
    New continuous production process for enantiopure (2R,5R)-hexanediol
    Organic Process Research & Development 6 (2002) 458-462
  • T. Stillger, M. Bönitz, M. Villela Filho, A. Liese
    Überwindung von thermodynamischen Limitierungen in substratgekoppelten Cofaktorregenerierungsverfahren
    Chemie Ingenieur Technik 74(7) (2002) 1035-1039
  • D. Kihumbu, T. Stillger, W. Hummel, A.Liese
    Enzymatic Synthesis of all Stereoisomers of 1-Phenylpropane-1,2-diol
    Tetrahedron Asymmetry 13 (2002) 69-1072
  • J. Haberland, A. Kriegesmann, E. Wolfram, W. Hummel, A. Liese
    Diastereoselective synthesis of optically active (2R,5R)-hexanediol
    Applied Microbiology & Biotechnology 58 (2002) 595-59
  • A. Liese, U. Kragl, H. Kierkels, B. Schulze
    Membrane reactor development for the kinetic resolution of ethyl 2-hydroxy-4-phenylbutyrate
    Enzyme Microbial Technology 30 (5) (2002) 673 – 681
  • C. Hoh, G. Dudziak, A. Liese
    Optimization of enzymatic synthesis of O-glycan core 2 structure by use of a genetic algorithm
    Bioorganic & Medicinal Chemistry Letters 12 (7) (2002) 1031-1034

2001

  • S. Laue, L. Greiner, J. Wöltinger, A. Liese
    Continuous application of chemzymes in a membrane reactor: Asymmetric transfer hydrogenation of acetophenone
    Advanced Synthesis & Catalysis 343 (6-7) (2001) 711-720
    DOI: 10.1002/1615-4169(200108)343:6/73.0.CO;2-1
  • C. Hoh, G. Dudziak, A. Liese (2001)
    Optimization of enzymatic synthesis of O-glycan core 2 structure by use of a genetic algorithm
    Bioorganic & Medicinal Chemistry Letters 12 (7), 1031-1034
  • N. Bézay, G. Dudziak, A. Liese, H. Kunz (2001)
    Chemoenzymatisch-chemische Synthese eines (2-3)-Sialyl-T-Threonin-Bausteins und dessen Einsatz in der Synthese der N-terminalen Sequenz von Leukämie-assoziierten Leikosialin (CD34)
    Angewandte Chemie 113 (12), 2350-2352
    Angewandte Chemie Int. Ed. 40, 2292-2295
    DOI: 10.1002/1521-3757(20010618)113:123.0.CO;2-R
  • N. Brinkmann, M. Malissard, M. Ramuz, U. Römer, T. Schumacher, E. G. Berger, L. Elling, C. Wandrey, A. Liese (2001)
    Chemo-enzymatic synthesis of the Galili epitope Gala(1,3)Galb(1,4)GlcNAc on a homogeneously soluble PEG polymer by a multi-enzyme system
    Bioorganic & Medicinal Chemistry Letters 11, 2503-2506
  • J.-S. Shin, B.-G. Kim, A. Liese, C. Wandrey (2001)
    Kinetic resolution of chiral amines with w-transaminase using an enzyme-membrane reactor
    Biotechnology & Bioengineering 73 (3), 179-187

2000

  • C. Wandrey, A. Liese, D. Kihumbu (2000)
    Industrial biocatalysis: Past, present and future
    Organic Process Research & Development 4, 286-290
  • G. Dudziak, N. Bézay, T. Schwientek, H. Clausen, H. Kunz, A. Liese (2000)
    Cyclodextrin- assisted glycan chain extension on a protected glycosyl amino acid
    Tetrahedron 56 (32), 5865-5869
  • H. Iding, P. Siegert, T. Dünnwald, M. Müller, L. Greiner, A. Liese, J. Grötzinger, A. Demir, M. Pohl (2000)
    Benzoylformate decarboxylase from Pseudomonas putida as stable catalyst for the synthesis of chiral 2-hydroxy ketones
    Chemistry – a European Journal 6 (8), 1483-1495
    DOI: 10.1002/(SICI)1521-3765(20000417)6:83.0.CO;2-S

1999

  • A. Liese, M. Villela Filho (1999)
    Production of fine chemicals using biocatalysis
    Current Opinion in Biotechnology 10 (6), 595-603
  • T. Zelinski, A. Liese, C. Wandrey, M.-R. Kula (1999)
    Asymmetric reduction in aqueous media: Enzymatic synthesis in cyclodextrin containing buffers
    Tetrahedron Asymmetry 10 (9), 1681-1687
  • A. Liese, T. Zelinski, M.-R. Kula, H. Kierkels, M. Karutz, U. Kragl, C. Wandrey (1998)
    A novel reactor concept for the enzymatic reduction of poorly soluble ketones
    Journal Molecular Catalysis B, Enzymatic 4, 91-99
  • A. Liese, M. Karutz, J. Kamphuis, C. Wandrey, U. Kragl (1996)
    Enzymatic resolution of 1-phenyl-1,2-ethanediol by enantioselective oxidation: Overcoming product inhibition by continuous extraction
    Biotechnology and Bioengineering 51, 544-550
    DOI: 10.1002/(SICI)1097-0290(19960905)51:53.0.CO;2-C

Other publications

  • L. Hilterhaus, J. Müller, A. Liese, M. Eckstein, O. Thum
    Kleine Gasblasen, große Wirkung
    Labor & More, 04/09, S. 12-14
  • A. Liese
    Industrielle Biotechnologie
    INGENIEUR-NACHRICHTEN 3/2007, S. 6
  • A. Liese, L. Hilterhaus
    Mehrstufenenzymprozesse
    Labor&More 01/07, S. 68-69
  • T. Becker, A. Liese, T. Maskow, A. Schippers, R. Takors, R. Ulber (2004)
    Biotechnologie ganz groß – In: Biotechnologie 2020 – Von der gläsernen Zelle zum maßgeschneiderten Prozess
    DECHEMA Broschüre des Zukunftsforums
  • A. Liese
    Biokatalyse – ein natürliches Prinzip für eine nachhaltige und resourcenschonende Chemie
    Process, 2012

Books

  • J. Tao, G.-Q. Lin, A. Liese
    Biocatalysis for the Pharmaceutical Industry
    Wiley-VCH, 2009, 1st edition, ISBN 0-470-82314-3
  • A. Liese, K. Seelbach, C. Wandrey
    Industrial Biotransformations
    Wiley-VCH, 2006, 2nd edition, 556 S., ISBN 3-527-31001-0
  • Industrial Biotransformations (Chinese ed.)
    2005, 1st edition
  • A. Liese
    Biological Principles Applied to Technical Asymmetric Catalysis
    Verlag Forschungszentrum Jülich, 2003, 207 S., ISBN 3-89336-344-0
  • A. Liese, K. Seelbach, C. Wandrey
    Industrial Biotransformations
    Wiley-VCH, 2000, 1st edition, 423 S., ISBN 3-527-30094-5

Book chapters

  • S. Baum, J. J. Müller, L. Hilterhaus, M. Eckstein, O. Thum, A. Liese
    The Bubble Column Reactor: A novel reactor type for cosmetic esters
    In: Applied Biocatalysis: From Fundamental Science to Industrial Applications
    Wiley-VCH (2016) 343-366
  • U. Sohling, K. Suck, P. Jonczyk, F. Sander, S. Beutel, T. Scheper, A. Thiefes, U. Schuldt, C. Aldenhoven, G. Egri, L. Dähne, A. Fiethen, H. Kuhn, O. Wenzel, H. Temme,
    B. Niemeyer, P. Bubenheim, A. Liese
    Inorganic adsorbents in enzymatic processes
    In: Applied Biocatalysis: From Fundamental Science to Industrial Applications
    Wiley-VCH (2016) 253-295
  • D. Gauss, B. Schönenberger, G. S. Molla, B. M. Kinfu, J. Chow, A. Liese, W. R. Streit,
    R. Wohlgemuth
    Biocatalytic phosphorylation of metabolites
    In: Applied Biocatalysis: From Fundamental Science to Industrial Applications
    Wiley-VCH (2016) 147-177
  • A. Liese, L. Pesci
    Enzyme classification and nomenclature and biocatalytic retrosynthesis
    In: Science of Synthesis: Biocatalysis in Organic Synthesis, Vol. 1
    Thieme (2015) SEITENANGABE ??
    ISBN: 9783131741318
    DOI: 10.1055/sos-SD-214-00028
  • L. Hilterhaus, A. Liese
    Industrial Application and Processes Forming C-O Bonds
    In: Enzyme Catalysis in Organic Synthesis, K. Drauz, H. Gröger, O. May (Ed.), 3rd edition, Vol. 1, 2, 3
    Wiley-VCH (2012)
  • R. Yuryev, L. Hilterhaus, A. Liese
    Industrial Applications and Processes Using Enzymes Acting on C-N Bonds
    In: Enzyme Catalysis in Organic Synthesis, K. Drauz, H. Gröger, O. May (Ed.), 3rd edition, Vol. 1
    Wiley-VCH (2012)
  • L. Hilterhaus, A. Liese
    Industrial Application and Processes Using Carbon-Carbon Lyases
    In: Enzyme Catalysis in Organic Synthesis, K. Drauz, H. Gröger, O. May (Ed.), 3rd edition, Vol. 1, 2, 3
    Wiley-VCH (2012)
  • K. Götz, L. Hilterhaus, A. Liese
    Industrial Application of Oxidoreductase catalyzed Reduction of Ketones and Aldehydes
    In: Enzyme Catalysis in Organic Synthesis, K. Drauz, H. Gröger, O. May (Ed.), 3rd edition, Vol. 1, 2, 3
    Wiley-VCH (2012)
  • L. Hilterhaus, A. Liese
    Industrial Application and Processes Using Biocatalysts for Oxidation Reactions
    In: Enzyme Catalysis in Organic Synthesis, K. Drauz, H. Gröger, O. May (Ed.), 3rd edition, Vol. 1, 2, 3
    Wiley-VCH (2012)
  • L. Hilterhaus, A. Liese
    Industrial Application and Processes Using Isomerases
    In: Enzyme Catalysis in Organic Synthesis, K. Drauz, H. Gröger, O. May (Ed.), 3rd edition, Vol. 1, 2, 3
    Wiley-VCH (2012)
  • A. van den Wittenboer, L. Hilterhaus, A. Liese
    Industrial Applications of Enzymes in Emerging Areas
    In: Enzyme Catalysis in Organic Synthesis, K. Drauz, H. Gröger, O. May (Ed.), 3rd edition, Vol. 1, 2, 3
    Wiley-VCH (2012).
  • S. Kara, A. Liese
    Enzymatic C-C Bond Formation, Asymmetric
    In: Encyclopedia of Industrial Biotechnology, D. Flickinger (Ed.)
    Wiley (2010)
  • L. Hilterhaus, A. Liese
    Biotransformation, Process Optimization, Kinetics and Engineering Aspects
    In: Encyclopedia of Industrial Biotechnology, D. Flickinger (Ed.)
    Wiley (2010)
  • L. Hilterhaus, A. Liese
    Bioprocess Development
    In: Manual of Industrial Microbiology and Biotechnology 3rd edition (Zhao, sect. ed.)
    (2008) ASM Press
  • L. Hilterhaus, A. Liese
    Applications of reaction engineering to industrial biotransformations
    In: Biocatalysis for the Pharmaceutical Industry (Tao, Lin, Liese eds.)
    Wiley (2009), 65-88
    ISBN 0-470-82314-3
  • U. Kragl, A. Liese
    Reaction on immobilized biocatalysts
    in Handbook of Heterogeneous Catalysis, 2nd Edition, Wiley-VCH, (2008)
  • A. Liese, S. Lütz
    Non-immobilized biocatalysts in industrial fine chemical synthesis
    in: Ullmann’s Biotechnology and Biochemical Engineering, 2 (2007) 735-755
  • L. Greiner, S. Laue, J. Wöltinger, A. Liese
    Continuous Asymmetric Hydrogenation
    in Topics in Current Chemistry: In Situ NMR Methods in Catalysis (Bargon, Kuhn), Springer-Verlag Berlin Heidelberg 2007, 111-124
  • M. Pohl, A. Liese
    Industrial processes using lyases for C-C, C-N, and C-O-bond formation
    in Patel: Biocatalysts in the Pharmaceutical and Biotechnology Industries (2007), 661-676
    CRC-Press, edited by R. Patel
  • S. Lütz, U. Kragl, A. Liese, C. Wandrey
    Reaction engineering in asymmetric synthesis
    in Asymmetric Synthesis with Chemical and Biological Methods (Enders, Jaeger), Wiley- VCH (2007), 415-427
  • R. Ulber, A. Liese, D. Sell, E. Flaschel
    Entwicklung der Weissen Biotechnologie in der deutschen Hochschullandschaft in Kooperation mit der Industrie
    in Fachbuch Weiße Biotechnologie, DBU, BIOCOM AG (2006) 67-75
  • S. Briechle, A. Liese, M. Howaldt, T. Roethig
    Enzymatische Prozesse in Bioprozesstechnik (Chmiel, ed.), Elsevier (2006), 361-408
  • L. Hilterhaus, A. Liese, M. Howaldt, H. Chmiel
    Enzymkinetik in Bioprozesstechnik (Chmiel, ed.), Elsevier (2006), 67-97
  • L. Greiner, A. Liese
    Hydrogenation and other reduction reactions
    in Multiphase Homogeneous Catalysis
    (Cornils, Herrmann, Vogt, Horvarth, Olivier-Bourbigou, Leitner, Mecking, eds), Wiley-VCH (2005), 819-834
  • A. Liese, S. Lütz (2004)
    Non-Immobilized Biocatalysts in industrial fine chemical synthesis
    in: Ullmann’s Encyclopedia of Industrial Chemistry, Wiley-VCH, 2 (2007) 735-755
  • B. Lingen, A. Liese, M. Müller (2003)
    Enantioselective synthesis of hydroxy ketones via benzaldehyde lyase- and benzoylformate decarboxylase-catalyzed C-C bond formation
    in Thiamine: Catalytic Mechanisms and Role in Normal and Disease States (M. S. Pate and F. Jordan, eds.) Marcel Dekker, New York (in press)
  • N. Rao, A. Liese (2003)
    Stereoselective synthesis with the help of recombinant enzymes
    in Molecular Biology in Medicinal Chemistry (Dingermann, Folkers, Steinhilber, eds.;
    Series: Methods and Principles in Medicinal Chemistry, series editors: K. Mannhold, H. Kubinyi, G. Folkers; Wiley-VCH, 125-152
  • A. Liese (2003)
    53 Keywords in Catalysis from A to Z
    (Cornils, Hermann, Schlögl, Wong, eds.) Wiley-VCH
  • A. Liese, S. Lütz (2002)
    Relevanz der Elektrochemie in oxidativen Biotransformationen
    GDCh Monographie der Fachgruppe Angewandte Elektrochemie: Elektronentransfer in Chemie und Biochemie
    (J. Russow, H.J. Schäfer) 23, 305-308
  • A. Liese (2002)
    Replacing chemical steps by biotransformations: Industrial application and processes using biocatalysis
    in Enzyme Catalysis in Organic Synthesis, 2nd edition, (K. Drauz, H. Waldmann, eds.), VCH-Wiley, 1419-1460
  • U. Kragl, A. Liese (1999)
    Biotransformations, engineering aspects
    in: The Encyclopedia of Bioprocess Technology: Fermentation, Biocatalysis & Bioseparation, eds. M. C. Flickinger and S. W. Drew, John Wiley & Sons, New York, 454-464

Patents

  • P. Bubenheim, G. Fieg, L. Hilterhaus, A. Liese, I. Smirnova, A. Sont,
    Use of a composition comprising silane compounds for coating column internals (preferably a plate, a package comprising several plates, a structured package and/or a filler body) used in reactive rectification
    Ein in der Reaktivrektifikation einsetzbarer, einen Biokatalysator aufweisende Kollonneneinbau und dessen Verwendung in der Reaktivrektifikation
    DE 102010028788A1
  • O. Thum, L. Hilterhaus, A. Liese
    Process for enzymatically preparing carboxylic esters
    US Application Serial No. 12/354,163 (0492717)
  • O. Thum, L. Hilterhaus, A. Liese
    Process for heterogeneously catalysed preparation of carboxylic acid derivatives
    US Application Serial No. 12/354,256 (0492720)
  • J. Beliczey, U. Kragl, A. Liese, C. Wandrey, H. Coenen, K. Hamacher and T. Tierling
    Enzymatic synthesis of 3-fluoroneuraminic acid (5-acetamido-3,5-didesoxy-3-fluoro-D- glycero-D-galacto-nonulopyranosonic acid) and other 3,5-didesoxy-3-fluorononulopyranosonic acid derivatives
    US 6,355,453 B1 (12.03.2002, patent application: US 09/156322, 18.09.1998)
  • S. Laue, A. Liese, C. Wandrey, O. Burkhardt, J. Woeltinger, A. Bommarius, H. Henniges, J.-L. Philippe, A. Karau, K. Drauz
    Use of molecular weight-enlarged catalysts in a process for assymetric, continuous hydrogenation, novel molecular weight-enlarged ligands and catalysts
    US 6,759,559 B1 (6.07.2004)
  • T. Stillger, M. Villela, A. Liese, C. Wandrey
    Verfahren und Vorrichtung zur enzymatischen Co-Faktoren-Regenerierung
    PT 1.1861 DE 100 60 602 (29.07.2005)

Patent applications

  • R. Yuryev, A. Liese
    Polyglycerin-gebundenes Bisoxazolin als wiederverwendbarer homogener Katalysator für die asymmetrische Synthese
    PT Nr. 10 2009 012 445.4, DE 10 2009 012 445 A1 (16.09.2010)
  • A. Liese, P. Bubenheim, K. Suck, U. Sohling, F. Ruf
    Verfahren zur Auftrennung von Alkohol-Keton-Gemischen
    DE 102009032080.6-43, 2009
  • O. Thum, L. Hilterhaus, A. Liese
    Verfahren zur enzymatischen Herstellung von Carbonsäureestern
    German patent application 102008004726.0, DE 2008P00002, 28.01.2008
  • O. Thum, L. Hilterhaus, A. Liese
    Verfahren zur heterogenkatalysierten Herstellung von Carbonsäurederivaten
    German patent application 102008004725.2, DE 2008P00003, 28.01.2008
  • M. de Oliviera Villela Filho, W. Hummel, C. Wandrey, A. Liese
    Verfahren zu Herstellung von Alkoholen aus Substraten mittels Oxidoreduktasen, Zweiphasensystem umfassend eine wässrige Phase und eine organische Phase sowie Vorrichtung zur Durchführung des Verfahrens
    DE 102 08 007.0 (26.02.2002, German patent application)
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